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Browse the research librarySmall-molecule NNMT (nicotinamide N-methyltransferase) inhibitor, 10mg per vial. Studied in preclinical metabolic research for its role in the NAD⁺ salvage pathway and adipocyte energy metabolism.
Listed Purity
99.00%
Method
HPLC
Certificate
Not published$10.50 / mg
In stock, ships from Sydney
For research use only. Not for human consumption. By purchasing this product, you confirm it will be used solely for legitimate research purposes.
Small-molecule NNMT (nicotinamide N-methyltransferase) inhibitor, 10mg per vial. Studied in preclinical metabolic research for its role in the NAD⁺ salvage pathway and adipocyte energy metabolism.
5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) — it is not a peptide. NNMT consumes the methyl donor SAM to methylate nicotinamide into 1-methylnicotinamide, diverting nicotinamide away from the NAD⁺ salvage pathway. In published preclinical work, inhibiting NNMT is associated with elevated intracellular NAD⁺ and SAM, reduced lipogenesis and smaller adipocytes in cell and diet-induced-obese rodent models, and is studied in the context of insulin sensitivity and muscle function. It is natively an orally-active compound. All figures and pathways described are preclinical research observations. For research use only. Not for human consumption.
